Institute of Bioinformatics

$Infractructure$

Vishalakshi Nanjappa, Ph.D.
Faculty Scientist

Institute of Bioinformatics
Discoverer Building, International Tech Park, Whitefield
Bangalore - 560 066
E-mail: vishalakshi at ibioinformatics dot org
Phone: +91-80-28416140 Fax: +91-80-28416132

Education

	Ph.D. in Cancer Biology, Institute of Bioinformatics, Bangalore, India and Amrita School of Biotechnology, Amrita Vishwa Vidyapeetham, Kollam, India
	M.Sc. in Microbiology, Bangalore University, Bangalore, India

Positions Held

	Faculty Scientist, Institute of Bioinformatics, Bangalore, India, 2022-Present
	DST-INSPIRE Faculty Fellow, Institute of Bioinformatics, Bangalore, India, 2019-2022
	DST-INSPIRE Faculty Fellow, Indian Institute of Science, Bangalore, India, 2017-2019
	Post-Doctoral Fellow, Institute of Bioinformatics, Bangalore, India, 2016-2017

Area of Specialization

	Proteomics
	Oncology

Publications

Research papers: 36

1. Jain, A. P.,Radhakrishnan, A., Pinto, S., Patel, K., Kumar M., Nanjappa, V., Raja, R., et al., (2021) How to Achieve Therapeutic Response in Erlotinib-Resistant Head and Neck Squamous Cell Carcinoma? New Insights from Stable Isotope Labeling with Amino Acids in Cell Culture-Based Quantitative Tyrosine Phosphoproteomics. OMICS A Journal of Integrative Biology. 25(9):605-616. [PubMed]

2. Nanjappa, V., Raja, R., Radhakrishnan, A., Jain, A.P., Datta, K.K., et al., (2018) Testican 1 (SPOCK1) and protein tyrosine phosphatase, receptor type S (PTPRS) show significant increase in saliva of tobacco users with oral cancer.Translational Research in Oral Oncology.[Article]

3. Rajagopalan, P., Patel, K., Jain, A. P., Nanjappa, V.,Datta, K. K., et al., (2018). Molecular alterations associated with chronic exposure to cigarette smoke and chewing tobacco in normal oral keratinocytes.Cancer Biology & Therapy 19(9):773-785.[PubMed]

4. Rajagopalan, P., Nanjappa, V.,Patel, K., Jain, A. P., Mangalaparthi, K. K., Patil, A. H., et al., (2018). Role of protein kinase N2 (PKN2) in cigarette smoke-mediated oncogenic transformation of oral cells. Journal of Cell Communication and Signaling. 12(4):709-721. [PubMed]

5. Nanjappa, V., Sathe, G.J., Jain, A. P., Rajagopalan, P., Raja, R, et al., (2017). Investigation of curcumin mediated signaling pathways in head and neck squamous cell carcinoma. Translational Research in Oral Oncology. [Article]

6. Radhakrishnan, A., Nanjappa, V.,Raja, R., Sathe, G., Puttamallesh, V. N., et al., (2016). A dual specificity kinase, DYRK1A, as a potential therapeutic target for head and neck squamous cell carcinoma. Sci Rep. 6:36132. [PubMed]

7. Rajagopalan, P#., Nanjappa, V.,Raja, R., Jain, A. P., Mangalparthi, K. K., et al., (2016). How does chronic cigarette smoke exposure affect human skin? A global proteomics study in primary human keratinocytes. OMICS: A Journal of Integrative Biology. 20:11, 615-626. [PubMed]

8. Nanjappa, V., Renuse, S., Sathe, G. J., Raja, R., Syed, N., et al., (2015). Chronic exposure to chewing tobacco selects for overexpression of stearoyl-CoA desaturase in normal oral keratinocytes. Cancer Biology and Therapy. 16(11):1593-603. [PubMed]

9. Nanjappa, V., Thomas, J. K., Marimuthu, A., Muthusamy, B., Radhakrishnan, A., et al., (2014). Plasma Proteome Database as a resource for proteomics research: 2014 update. Nucleic Acids Research. 42(Database issue):D959-65. [PubMed]

10. Nanjappa, V., Raju, R., Muthusamy, B., Sharma, J., Thomas, J. K., et al., (2011). A comprehensive curated reaction map of leptin signaling pathway. Journal of Proteomics and Bioinformatics. 4(9), 184-189. [Article]

Research Support

	Title of Project		Funding Agency		Role
1	Identification of signaling mechanisms and alternative Therapies in head and neck squamous cell carcinoma Resistant to cisplatin		Department of Science and Technology		PI

Member

Member of Society of Biological Chemists INDIA, Indian Institute of Science, Indian Institute of Science